Ginkgo biloba
Content by: OpenSupplement Editorial Team | Medical review: pending | Last updated: April 13, 2026
TL;DR
One of the oldest living tree species; used for blood flow and memory
Moderate evidence for improving symptoms in existing dementia
Low evidence for preventing dementia or treating tinnitus
Acts as a powerful vasodilator (opens blood vessels)
Significant blood-thinning properties; use caution
Cost: ~$8-15/month
Best for: Peripheral circulation, supporting existing cognitive decline
What it is
Ginkgo extract (specifically the standardized EGb 761 form) contains flavonoids and terpenoids that improve blood flow to the brain and extremities. It also acts as an antioxidant, protecting nerves from oxidative stress.
What the research says
Ginkgo is a staple in tinnitus forums. Evidence. Despite many anecdotes, a large Cochrane review concluded that there is no clear evidence that Ginkgo helps tinnitus for the majority of people, unless the tinnitus is specifically caused by blood flow issues in the inner ear. [1]
The evidence for Ginkgo is 'split.' Existing Dementia. For those already experiencing cognitive decline, meta-analyses show that high-dose Ginkgo (240mg) can improve symptoms as effectively as some pharmaceutical drugs. Prevention. However, large trials (like the GEMS study) showed that it does not prevent Alzheimer's in healthy people. It's better as a treatment than a preventative. [2][3]
Theoretical benefit via cochlear blood flow improvement. Limited direct hearing loss trials. Most evidence is from tinnitus studies with hearing outcomes as secondary endpoints.
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Ginkgo biloba on Amazon
Safety
Generally safe, but it is a potent blood thinner. It can increase the risk of spontaneous bleeding (like nosebleeds) and should never be combined with aspirin or warfarin without medical supervision.
Interactions
- Blood Thinners: Major interaction; avoid Warfarin, Eliquis, Aspirin.
- Seizure Meds: May lower the seizure threshold.
Dosing
Standard Dose: 120-240 mg daily of standardized extract (24% flavone glycosides). Timing: Split into two doses.
Cost
Affordable. $8-15 per month.
The bottom line
Ginkgo is a circulation specialist. It's helpful for keeping an aging brain 'well-fed' with blood, but it's not a silver bullet for memory or ear ringing.
References
- Hilton MP, Zimmermann EF, Hunt WT. Ginkgo biloba for tinnitus. Cochrane Database Syst Rev. 2013;3:CD003852.
- Vellas B, Coley N, Ousset PJ, et al. Long-term use of standardised Ginkgo biloba extract for the prevention of Alzheimer's disease (GuidAge): a randomised placebo-controlled trial. Lancet Neurol. 2012;11(10):851-9.
- Birks J, Grimley Evans J. Ginkgo biloba for cognitive impairment and dementia. Cochrane Database Syst Rev. 2009;1:CD003120.
Sources for this page include published meta-analyses, systematic reviews, and NIH dietary supplement fact sheets. All claims reflect the evidence as of early 2026.
This is not medical advice. Consult your healthcare provider before starting any supplement, especially if you take medications.